Lamp2是什么
Tīmeklis2024. gada 16. marts · 针对溶酶体标志物Lamp-1 和 Lamp-2,或吞噬泡及自噬小体的标志物 Atg5,Atg14,Beclin-1的抗体经常被用在免疫荧光显微镜上、western blot及流式细胞仪上追踪自噬过程的进展。 Lamp-2的检测 (图3) 应该与LC3-II检测联用，因Atg14也与ER关联它的检测也需要与其它标志物检测联用。 image Tīmeklis2024. gada 7. nov. · Lamp2 knockout (KO) mice are characterized by disrupted autophagy and phagocytosis in hepatocytes, neurons, and leukocytes (23–26). Loss-of-function mutations of the human LAMP2 gene cause Danon disease, a lysosomal storage disorder characterized by cardiomyopathy, skeletal myopathy, and mental …
Lamp2是什么
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Tīmeklis小鼠lamp2基因缺陷能减少高脂饮食诱导的肥胖 ，说明lamp2在肝细胞脂代谢中具有重要作用。 此外，LAMP2已被报道在甲状腺素诱导的肝细胞脂代谢中表达上调 [ 12 ] … TīmeklisCells that lack LAMP2 express normal levels of VAMP8, but fail to accumulate STX17 on autophagosomes, which is the most likely explanation for the lack of fusion between autophagosomes and lysosomes (PubMed:27628032). Required for normal degradation of the contents of autophagosomes (PubMed:27628032).
Tīmeklis2024. gada 1. janv. · A database linking antimicrobial peptides (LAMPs), launched in 2013, serves as a comprehensive tool to supply exhaustive information of AMP on a single platform. LAMP2, an updated version of LAMP, holds 23 253 unique AMP sequences and expands to link 16 public AMP databases. In the current version, …
Tīmeklis2024. gada 21. marts · LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. Diseases associated with LAMP2 include Danon Disease and Left … TīmeklisLAMP2. LAMP2 mutations produce the multisystemic disorder, Danon disease, in which neurologic, skeletal muscle, and hepatic involvement occur with cardiomyopathy. …
TīmeklisThe LAMP2 gene provides instructions for making a protein called lysosomal associated membrane protein-2 (LAMP-2), which, as its name suggests, is found in the …
Tīmeklis2024. gada 23. jūn. · LAMP2基因9号外显子的剪切差异可致所编码的LAMP2蛋白存在LAMP2A、LAMP2B及LAMP2C 3种亚型，区别仅在于溶酶体羧基末端跨膜区域及胞 … is it safe to eat sushi the next dayTīmeklismTOR信号通路[2] mTORC1促进细胞生长的过程主要由生长因子、能量状态、含氧量和氨基酸等多种信号调节。参与调节mTORC1活性的最重要蛋白质是结节性硬化症复 … is it safe to eat sushi everydayTīmeklis2024. gada 25. aug. · LAMP2, an updated version of LAMP, holds 23 253 unique AMP sequences and expands to link 16 public AMP databases. In the current version, there are more than 50% (12 236) sequences only linking a single database and more than 45% of AMPs linking two or more database links. is it safe to eat sweetened condensed milkTīmeklisLatent Membrane Protein 2 (LMP2) LMP2A is an EBV-encoded protein with three domains: (a) an N-terminal cytoplasmic domain, which has PY motifs that bind to WW domain-containing E3 ubiquitin ligases and an ITAM that binds to SH2 domain-containing proteins, (b) a transmembrane domain with 12 transmembrane segments … keto salmon air fryer recipesTīmeklisLAMP2 (D5C2P) Rabbit mAb 可识别 LAMP2 总蛋白的内源水平。 物种反应性： 人 来源/纯化 使用人 LAMP2 蛋白氨基端特异的重组蛋白对动物进行免疫接种来产生单克隆抗体。 背景 溶酶体相关膜蛋白 1 和 2（LAMP1 和 LAMP2）是两种含量丰富的溶酶体膜蛋白 (1,2)。 两者都是跨膜蛋白，并且在溶酶体的内腔面氨基末端被高度糖基化，这能 … is it safe to eat tartareTīmeklis利用工程化胞外体的亲本细胞方法，最常见的将蛋白质引导到胞外体表面的方法是使用 胞外体信号肽 。 例如，溶酶体相关膜蛋白2b（Lamp2b）是具有信号肽的胞外体表面 … keto salisbury steak with onion gravyTīmeklisA. The quantification of the colocalization between a lysosomal protein such as LAMP2 and LC3 could be used via a standard immunofluorescence protocol (fixation using 4% PFA (10 min) and permeabilization using 0.1% Triton X-100 (5 min)) as an alternative method to monitor autophagic flux. The primary antibodies used for this alternative … keto salmon recipes air fryer