Nucleophosmin phosphorylation

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August undefined, 2024

Web3 mei 2016 · Dephosphorylated NPM impairs the signaling of oxidative stress-induced DNA damage via inhibition of the phosphorylation of ataxia-telangiectasia mutated and DNA … • Yun C, Wang Y, Mukhopadhyay D, Backlund P, Kolli N, Yergey A, Wilkinson KD, Dasso M (November 2008). "Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases". The Journal of Cell Biology. 183 (4): 589–95. doi:10.1083/jcb.200807185. PMC 2582899. PMID 19015314. • Haindl M, Harasim T, Eick D, Muller S (March 2008). "The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of n…

Nucleophosmin Phosphorylation as a Diagnostic and Therapeutic …

Web1 jul. 2006 · Nucleophosmin (encoded byNPM1) is frequently overexpressed, mutated, rearranged and deleted in human cancer. NPM has many functions, so how does either … Web1 sep. 2024 · Nucleophosmin Phosphorylation as a Diagnostic and Therapeutic Target for Ischemic Acute Kidney Injury Journal of the … poems that reference greek mythology

Nucleophosmin and human cancer - PubMed

Web11 mrt. 2024 · Figure 1. Dual specificity phosphatase 3 (DUSP3) binds with high affinity to nucleophosmin (NPM) in vitro and affects its nuclear localization and tyrosine … WebNPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, … Web27 jun. 2014 · NPM1 is phosphorylated by various kinases during different stages of the cell cycle [6]. NPM1 associates with unduplicated centrosomes, but upon phosphorylation … poems that talk about death

Recombinant AP Anti-Nucleophosmin (phospho S125) antibody …

Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV …

WebThese findings indicate the involvement of nucleophosmin in the regulation of pre-mRNA processing, and its activity is controlled by CDK2-mediated phosphorylation on Thr(199). These results demonstrate a novel mechanism for transcriptional regulation of E2F1 and identify the functional role of nucleophosmin/B23 in modulating the binding of NF … Web1 jan. 2024 · An example of order to disorder transition is nucleophosmin (NPM1), sequential phosphorylation of solvent exposed Ser and Thr regulates the … poems that say i miss youWeb31 jan. 2011 · Nucleophosmin (NPM) is a multi-functional cellular chaperone NPM is the product of the NPM1 gene, which in humans contains 12 exons and maps to … poems that say thank you

"Web19 mrt. 2010 · PDF Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV latency. (0.05 MB DOC) Find, read and cite all the research you need on ResearchGate " - Nucleophosmin phosphorylation

Nucleophosmin phosphorylation

Recombinant HRP Anti-Nucleophosmin (phospho T199) antibody …

WebIn BriefSmall molecule HIV-1 transcription inhibitor, 1E7-03, that binds to the noncatalytic RVxF accommodating site of protein phosphatase 1 reprogramed protein … WebNucleophosmin Phosphorylation by v-Cyclin-CDK6 Controls KSHV Latency Grzegorz Sarek1, Annika Ja¨rviluoma1, Henna M. Moore2, Sari Tojkander2, Salla Vartia1, Peter …

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WebThe kinase activity of cyclin-dependent kinase 2 (CDK2)-cyclin E is required for centrosomes to initiate duplication. We have recently found that nucleophosmin (NPM/B23), a … Web30 jun. 2015 · Phosphorylation inhibition causes greater G2/M arrest of cells with only one centrosome in NPMc-overexpressing cells than wtNPM and GFP counterparts As …

WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity … WebThe nucleophosmin gene (NPM1 ), located at chromosome region 5q35, encodes a nucleocytoplasmic shuttling protein with prominent nucleolar localization. NPM1 …

WebAbstract. Nucleophosmin (NPM) is a nucleolar phosphoprotein that shuttles between the nucleus and cytoplasm during the cell cycle. NPM has several interacting … Web1 dec. 2024 · Phosphorylation [37, 78], as well as glutathionylation [14], have been reported to signal NPM1 nucleolar exit. On one hand, phosphorylation at Thr199 or …

Web1 jan. 2013 · Phosphorylation of nucleolin by a yet unidentified protein kinase dependent on Rho-associated kinase (ROCK) leads to translocation of nucleolin from the nucleolus …

Web22 dec. 2015 · Upon analysis, we found phosphorylated level of nucleophosmin (NPM) at Threonine 234/237 (p-NPM-Thr234/237) had remarkably high level in metastatic … poems that take 1 minute to readWeb31 aug. 2010 · Here, we report a new role for the nucleophosmin protein NPM1 in these mechanisms. Thr199-phosphorylated NPM1 (pT199-NPM1) is recruited to nuclear DNA … poems that use abab rhyme schemeWeb20 dec. 2024 · Differential nucleophosmin (NPM) phosphorylation is a potential early marker of ischemic renal cell injury and a therapeutic target. Methods Differential NPM … poems that use alliterationWeb11 nov. 2015 · Nucleophosmin (NPM) is an abundant phosphoprotein predominantly localized in nucleoli, involved in many distinct biological processes including ribosome … poems that use allegoryWeb19 mrt. 2010 · Author Summary Latency is the predominant mode of viral persistence in KS and PEL tumors, and has a fundamental impact on KSHV tumorigenesis. Establishment … poems that use anaphoraWeb2 mei 2016 · The signal transducer and activator of transcription 3 (STAT3) can be activated by the tyrosine kinase domain of the chimeric protein … poems that will make your dad cryWeb总之，我们的研究结果揭示核仁蛋白在核仁应激因素下可以通过感应核仁区室的氧化信号、发生定位改变，通过激活或阻断特定信号通路，介导核仁应激应答反应。这些发现阐释了核仁区室作为细胞应激感受器的分子基础。展开著录项作者杨凯; 作者单位上海交通大学; 授予单位上海交通大学; 学科细胞生物学授予学位博士导师姓名易静; 年度 2014 页码总 … poems that use consonance